Histopathologic changes seen during the reopening of the intestinal lumen after obliteration of the digestive tract with nonabsorbable material. Experimental study in the rat

: The constant pressure exerted by occlusive ligation on the intestinal wall produces ischemia and ulceration of the mucosa, interruption of the muscular layer and transmural inflammatory reaction, which terminates when the ligature is eliminated and the injured tissues are repaired.