Isolation and structure of the powerful human cancer cell growth inhibitors spongistatins 4 and 5 from an African Spirastrella spinispirulifera(porifera)
1993
The Southwest Indian Ocean marine sponge Spirastrella spinispirulifera has been found to contain (in 10–7% yields) two extraordinarily potent (Gl50ca. 10–8µg ml–1) human cancer cell line inhibitors designated spongistatins 4 1d and 5 2.
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