Abstract WP431: Functionally Distinct Neuronal Nitric Oxide Synthase Expressed in the Brain Microvascular Endothelial Cells Mediates Anoxic-injury to Blood-Brain Barrier

Venkata N. Sure,Nicholas R. Peterson,Allen L. Chen,Neelesh P Jain,Graham D. Unis,Tyler Pierce Baker,Angellica O Gordon,Ivan Merdzo,Ibolya Rutkai,David W. Busija,Prasad V. G. Katakam

Abstract WP431: Functionally Distinct Neuronal Nitric Oxide Synthase Expressed in the Brain Microvascular Endothelial Cells Mediates Anoxic-injury to Blood-Brain Barrier

2017

Venkata N. Sure
Nicholas R. Peterson
Allen L. Chen
Neelesh P Jain
Graham D. Unis
Tyler Pierce Baker
Angellica O Gordon
Ivan Merdzo
Ibolya Rutkai
David W. Busija
Prasad V. G. Katakam

Objective: Mice with genetic deletion of endothelial (eNOS; protective) and neuronal (nNOS; detrimental) nitric oxide synthase isoforms exhibit dramatically opposite consequences of ischemic brain ...

Keywords:

Physical therapy
Blood–brain barrier
Endocrinology
Nitric oxide synthase
Gene isoform
Neuronal Nitric Oxide Synthase
Diabetes mellitus
Enos
Nitric oxide
Medicine
Internal medicine
ischemic brain

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