CYANOACRYLATE GLUE IN SOCKET REPAIR: A COMPARATIVE STUDY

Abstract This study aims to compare socket repair after tooth extraction and suture using Nylon 5-0 versus closure using cyanoacrylate biologic glue. Twenty male Wistar rats were used, with each animal weighing approximately 200 g. They were submitted to the extraction of the right and left first molar teeth. On the right side, the alveolus closure was performed with a 2 ethyl-cyanoacrylate, whereas on the left side a single interrupted suture was performed with Nylon 5-0. The animals were sacrificed after 3, 7, 15, and 30 postoperative days, and images of histological sections of the alveolus were captured for analysis. Histomorphometry was performed using Image J software to quantify bone neoformation in the alveolus. The results showed that on the 7th postoperative day, the side that received the 2-ethyl-cyanoacrylate presented a delay in relation to the sutured side. However, on days 15 and 30 of the postoperative period, the difference in bone neoformation between both studied sides gradually decreased until the 30th postoperative day, with no significant difference to bone neoformation in the last period of analysis. There was no difference between the bone neoformation in the sutured alveolus and the other side that received cyanoacrylate glue (p = 0.902) after statistical analysis of the histomorphometric results. In conclusion, socket repair after alveolus closure with 2-ethyl-cyanoacrylate allows a complete bone neoformation after tooth extraction, and there is no significant difference when compared to Nylon 5-0.