The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway

Dongke Yu,Caixia Zhang,Shuangshuang Zhao,Shenghua Zhang,Hao Zhang,Shi-Ying Cai,Rongguang Shao,Hongwei He

The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway

2015

Dongke Yu
Caixia Zhang
Shuangshuang Zhao
Shenghua Zhang
Hao Zhang
Shi-Ying Cai
Rongguang Shao
Hongwei He

The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway

Keywords:

SMAD
Protein kinase B
Cancer research
PI3K/AKT/mTOR pathway
Hepatic stellate cell
Bile duct
Signal transduction
Cholestasis
Cell culture
Endocrinology
Biochemistry
Medicine
Internal medicine
Inflammation
Fibrosis
TIMP1
Pharmacology

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