EVALUATION OF ANTIULCER ACTIVITY OF IPOMOEA STAPHYLINA

Summary The ethalonic extract of leaves of Ipomoea staphylina (Convolvulaceae) was investigated for its antiulcer activity in wistar rats. Ipomoea staphylina (500 mg/kg, p.o) or ranitidine (50 mg/kg p.o) in pylorus ligation induced gastric ulcer method, the ethanol extract of Ipomoea staphylina showed significant reduction in gastric volume(P<0.01), free acidity (P<0.001), total acidity (P<0.001) and ulcer score (P<0.001) as compared to control (Table-1). In ethanol induced ulcers in rats, the ethanol extract of Ipomoea staphylina showed significant reduction in gastric lesion (P<0.001).