Peritoneal Dialysis-Related Peritonitis:Pathogenic Bacteria and Its Drug Resistance Analysis

Objective To explore the pathogenic bacteria causing peritoneal dialysis-related peritonitis and its drug sensitivity.Methods 69 cases suffering peritoneal dialysis-related peritonitis were analyzed retrospectively about the pathogenic bacteria,drug susceptibility test,curative effect and prognosis.Results Of the peritoneal fluid culture of the 69 patients,48 were found positive and the positive rate was 69.60%,among which 19 cases(39.59%) were infected with gram positive cocci,18 cases(37.50%) with gram negative cocci and 11 cases(22.91%) with fungi.Drug sensitivity test results showed that gram positive cocci was sensitive to vancomycin in all cases,but it has the highest resistance rate to penicillin(80.00%).It was also resistant to oxacillin and levofloxacin(63.64% and 52.63% respectively).Gram negative bacilli were sensitive to lmipenem in all cases,but they had the highest resistance rate of 75.00% to ampicillin and a low resistance rate of 18.75% to gentamicin.Candida parapsilosis had the highest proportion in fungal.The patients infected with gram positive cocci peritonitis usually had a good prognosis,but those with fungal peritonitis had a bad prognosis.Conclusion Gram positive cocci is still the main pathogen causing peritoneal dialysis-related peritonitis,but the proportion of peritonitis caused by gram negative bacilli and fungi increases dramatically.The fungi peritonitis has a bad prognosis,therefore effective prevention measurements are needed.