Haloacetyl derivatives of styrene-divinylbenzene copolymers as carriers for the immobilization of enzymes☆

Styrene-divinylbenzene copolymers with various structures have been used as the basis for synthesizing compounds with mobile halogen atoms: these are the copolymers' brom- and iodoacetyl derivatives which have been used as polymeric carriers for the immobilization of glucoamylase and pepsin. The effect of the copolymers' macromolecular structure and the halogen content on the process of immobilizing glucoamylase and pepsin has been studied. It has been shown that the iodoacetyl derivatives of the styrene-divinylbenzene copolymers with a macro-porous structure and a high iodine content are the most suitable for immobilizing these enzymes.