Polyaniline Supported FeCl 3 : An Effective Heterogeneous Catalyst for Biginelli Reaction

Polyaniline supported FeCl3 is prepared and tested as an efficient heterogeneous Lewis acidic catalyst for the Biginelli reaction. The catalyst PANI–FeCl3 shows excellent activity in the synthesis of dihydropyrimidinones from aldehydes in the three component reaction with urea and β-keto esters or 1,3-diketones. The catalyst was characterized by usual analytical and spectroscopic techniques.