Autoantibody presentation in drug-induced liver injury and idiopathic autoimmune hepatitis: the influence of human leucocyte antigen alleles.

Camilla Stephens,A. Castiella,Gomez-Moreno Em,P. Otazua,Miguel-Ángel López-Nevot,Eva Zapata,A. Ortega-Alonso,Francisco Ruiz-Cabello,I. Medina-Cáliz,M. Robles-Díaz,Germán Soriano,E. Román,H. Hallal,J.M. Moreno-Planas,M. Prieto,R.J. Andrade,M.I. Lucena

Autoantibody presentation in drug-induced liver injury and idiopathic autoimmune hepatitis: the influence of human leucocyte antigen alleles.

2016

Camilla Stephens
A. Castiella
Gomez-Moreno Em
P. Otazua
Miguel-Ángel López-Nevot
Eva Zapata
A. Ortega-Alonso
Francisco Ruiz-Cabello
I. Medina-Cáliz
M. Robles-Díaz
Germán Soriano
E. Román
H. Hallal
J.M. Moreno-Planas
M. Prieto
R.J. Andrade
M.I. Lucena

ObjectivesPositive autoantibody (AAB) titres are commonly encountered in autoimmune hepatitis (AIH) and in a proportion of drug-induced liver injury (DILI) patients. The underlying mechanism for selective AAB occurrence in DILI is unknown, but could be associated with variations in immune-associated

Keywords:

Autoantibody
Drug
Autoimmune hepatitis
Liver injury
Biology
Allele
Immunology
Human leucocyte antigen

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