Methods for enhancing adjuvanticity vaccine compositions

A vaccine composition comprising: a) a compound 5 PBS-57 of formula: ** ** Formula b) an antigen for use as a medicament in a method for enhancing the humoral immune response and / or cell-mediated antigen a subject immunized with said vaccine composition, with respect to a control of a subject immunized with said antigen alone, and wherein the antigen is complexed with the B subunit of Shiga toxin or a functional equivalent thereof which is able binding to the receptor Gb3.