Increased Release of the N-Terminal and C-Terminal Portions of the Atrial Natriuretic Factor Prohormone during Immersion-Induced Central Hypervolemia in Cirrhotic Humans

The role of peptides from the N-terminus and C-terminus of the 126 amino acid (a.a.) atrial natriuretic factors (ANF) prohormone in modulating renal sodium and water handling in cirrhotic patients has