Effect of Butyric or Lactic Acid on the In vivo Colonization of Salmonella typhimurium

Abstract Two groups of newly hatched chicks received standard broiler rations supplemented with 0.6% acid (either butyric or lactic) continuously starting at one day of age, while a control group received unsupplemented feed. At two days of age, chicks were inoculated by oral gavage with 1 mL of 106 CFU Salmonella typhimurium. Ceca were obtained from six chicks of each group at day 7, 14, and 21. After seven days there were no differences in level of Salmonella colonization among the supplemented and control groups. After fourteen days, lactic acid decreased colonization by 1.6 logs (P