[P144] Mycosis fungoides arising on severe atopic dermatitis : a case report with emphasis on their association

Atopic dermatitis (AD) is a chronic inflammatory disorder that has increased in prevalence over the past 30 years. This disease is well known for its waxing and waning course, often showing prolonged symptoms. Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma and has a prolonged and progressive course characterized by patches, plaques, and tumor stages. Several studies have investigated the possible association between atopic eczema and cancer, yielding very controversial results. A 35-year-old female presented with disseminated erythematous scaly plaques on most of her body for 8 years. Based on the clinical findings of chronic pruritic plaques along with the histologic evidence of lichen simplex chronicus, atopic dermatitis was diagnosed. 15 months after various kinds of immunosuppressant treatment, a few intractable scaly plaques were left on her nose and thigh, which were finally confirmed as MF. Herein, we report a case of MF without circulating Sezary cells diagnosed 8 years after adult-onset severe atopic dermatitis.