Complete enantioseparation through supramolecular complex formation between tris(1,3-diaminopropane)cobalt(III) phosphate and β-cyclodextrin, [Co(tn)3]PO4·β-CDX.

The supramolecular complex [Co(tn) 3 ]PO 4 ·β-CDX (tn = 1,3-diaminopropane ; β-CDX = β-cyclodextrin) was prepared through β-CDX, rac-[Co(tn) 3 ]Cl 3 , and Na 3 PO 4 in a mole ratio of 1:2:2. After one recrystallization process, the circular dichroism spectrum confirmed that complete enantioseparation of [Co(tn) 3 ]PO 4 is achieved in this system. X-ray crystal structure analysis reveals the presence of the only A-enantiomer in the unit cell and the head-to-head chiral discrimination structure of this system. Thus, we found that the present diastereomer formation with β-CDX affords the very convenient and effective optical resolution procedure of [Co(tn) 3 ] 3+ . .