Myocardial extraction of technetium-99m-[2-(1-methoxybutyl) isonitrile] in the isolated rabbit heart: a myocardial perfusion agent with high extraction and stable retention.

0.71± 0.07,PS@,= 2.21± 0.76mL/mln . g, p < 0.0001), the net extrac@on of @Fc-MBI (E@ = 0.52 ±0.10)was only slightlylessthanthevaluefor @@h11 (E@= 0.56±0.10,p < 0.05).There was no significantdifferenceinthe myocerd@up take versus flow between @rc-MBI and @@111. These data lnd@ate that assessmentof relabvecoronaryflow basedon the myocerd@ uptake of @rc-MBl shouldgWe resufts comparable to 20111. Therefore, @c-MBI may havedinical poterthalas a radiolabeled myocardial perfusion agent. J NucIMed1993;34:927-931