COMPARAÇÃO DO PERFIL DE ANTICORPOS ANTI- IMUNOGLOBULINA G EM MURINOS IMUNIZADOS COM IgG HUMANA ASSOCIADA A DIFERENTES ADJUVANTES Comparing the profile of anti-immunoglobulin G in murine immunized with human IgG associated with different adjuvants

Adjuvants are substances associated with antigens that increase or modify the imune response. This work/study is a comparison of the profile of murine antibodies in groups immunized with human IgG associated or not with adjuvants, using the Enzyme Linked Immunosorbent Assay (ELISA) technique in the 28 th and 40 th days after immunization. The adjuvants evaluated in this work/study were the aluminium hydroxide and Freund's adjuvant. The results showed that in 28 th day the mice immunizad with adjuvants exhibited higher values of absorbance compared with the animals immunized without adjuvants. However, it was found that the murine immunized with aluminium hydroxide and Freund's adjuvant showed similar values of optical density. In contradiction, in the 40 th day the groups of mice examined showed analogues profiles of anti-human IgG .