The Binding of 4-Cyano-N,N-dimethyl-[14C] aniline (CDA) Metabolites to Macromolecules in Mice Exposed to CDA

S. Edwards,D. Hesk,C. J. Logan,R. Waters

The Binding of 4-Cyano-N,N-dimethyl-[14C] aniline (CDA) Metabolites to Macromolecules in Mice Exposed to CDA

1985

S. Edwards
D. Hesk
C. J. Logan
R. Waters

This paper indicates that in mice the reactive metabolites of CDA bind to proteins and nucleic acids. Radiolabel was found associated with DNA from the liver, kidney and testes of treated animals.

Keywords:

Sodium acetate
DNA
Macromolecule
Nucleic acid
Aniline
Biochemistry
Organic chemistry
Chemistry
Kidney
reactive metabolite
Stereochemistry

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