Effects of bicarbonate therapy on hemodynamics and tissue oxygenation in patients with lactic acidosis: a prospective, controlled clinical study.

ObjectiveTo determine whether correction of acidemia using bicarbonate improves hemodynamic variables and tissue oxygenation in patients with lactic acidosis.DesignProspective, randomized, blinded, cross over study. Each patient sequentially received sodium bicarbonate and sodium chloride. The order