Low molecular weight (LMW) orally bioavailable inhibitors of tumor vascular endothelial growth factor (VEGF) translation delay tumor growth in vivo: A new approach to inhibition of angiogenesis.

3123 Background: VEGF plays a critical role in the pathogenic angiogenesis associated with a number of diseases including cancer. Blockade of VEGF by a humanized monoclonal antibody or by inhibitor...