P161 Prognostic value of pretreatment neutrophil–lymphocyte ratio in metastatic breast cancer

2015 
Goals: Adenoid cystic carcinoma (ACC) of the breast is rare. The aim of this study is to review cases of ACC treated in a DGH. Methods: This database was searched for all cases of ACC of the breast from January 2002 to December 2013. Their demographics, tumour characteristics, treatment and survival were reviewed. Results: There were 9 patients giving an incidence of 0.1%. The mean age at diagnosis was 65 years (53–82). The mean tumour size was 2.48 cm (1.5–5 cm). The tumour grading: GI 6, GII 2, GIII 1. 7 patientswere oestrogen receptor (ER) negative and two ERpositive. All were progesterone receptor (PR) negative (1 unrecorded). 6 of the patients were HER2 receptor negative (3 unrecorded). 7 were node negative (2 unrecorded). Of 7 patients who had surgery, two had mastectomies and five wide local excisions. 4 patients received radiotherapy and none chemotherapy. Mean follow up was 36 months (3–69). There was 1 breast cancer death in a patient with advanced disease. Conclusion: Adenoid cystic carcinomas of the breast are rare, tend to be triple negative and node negative and have a favourable prognosis. They may represent a subset of patients who can be treated with less axillary surgery and less chemotherapy. Disclosure of Interest: No significant relationships.
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