PI3K inhibition as a novel therapeutic strategy for neoadjuvant chemoradiotherapy resistant oesophageal adenocarcinoma

Sarah D. Edge,Isaline Renard,Emily Pyne,Chun Li,Hannah Moody,Rajarshi Roy,Andrew W Beavis,Stephen J. Archibald,Christopher Cawthorne,Stephen G. Maher,Isabel M. Pires

PI3K inhibition as a novel therapeutic strategy for neoadjuvant chemoradiotherapy resistant oesophageal adenocarcinoma

2021

Sarah D. Edge
Isaline Renard
Emily Pyne
Chun Li
Hannah Moody
Rajarshi Roy
Andrew W Beavis
Stephen J. Archibald
Christopher Cawthorne
Stephen G. Maher
Isabel M. Pires

Objective:Neoadjuvant chemoradiotherapy (neo-CRT) prior to surgery is the standard of care for oesophageal adenocarcinoma (OAC) patients. Unfortunately, most patients fail to respond to treatment. ...

Keywords:

Internal medicine
therapeutic strategy
neoadjuvant chemoradiotherapy
Oncology
standard of care
Oesophageal adenocarcinoma
MEDLINE
Medicine

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