Design of new anticancer drugs. I. Easy hetarynic access to dihydrodipyridopyrazines, a new family of antitumor agents
1998
Abstract Unprecedented dihydrodipyridopyrazines were easily obtained by hetarynic dimerization of 2-alkylamino-3-bromopyridines in the presence of the complex base NaNH 2 - t BuONA. A few chemical properties of these new heterocycles are reported, as well as their antitumoral activity.
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