Two‐Photon‐Triggered Drug Delivery in Cancer Cells Using Nanoimpellers

Jonas G. Croissant,Marie Maynadier,Audrey Gallud,Harmel W. Peindy Ndongo,Jeff L. Nyalosaso,Gaelle Derrien,Clarence Charnay,Jean-Olivier Durand,Laurence Raehm,Françoise Serein-Spirau,Nathalie Cheminet,Thibaut Jarrosson,Olivier Mongin,Mireille Blanchard-Desce,Magali Gary-Bobo,Marcel Garcia,Jie Lu,Fuyuhiko Tamanoi,Derrick Tarn,Tania M. Guardado-Alvarez,Jeffrey I. Zink

Two‐Photon‐Triggered Drug Delivery in Cancer Cells Using Nanoimpellers

2013

A therapy of cancer cells: Two-photon-triggered camptothecin delivery (see picture) with nanoimpellers was studied in MCF-7 breast cancer cells. A fluorophore with a high two-photon absorption cross-section was first incorporated in the nanoimpellers. Fluorescence resonance energy transfer (FRET) from the fluorophore to the azobenzene moiety was demonstrated.

Keywords:

Azobenzene
Organic chemistry
Drug delivery
Cancer
Two-photon excitation microscopy
Cancer cell
Förster resonance energy transfer
Fluorophore
Camptothecin
Chemistry

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations