Short-term efficacy of percutaneous vascular forming and stenting in patients with severe stenosis combined with cerebral infarction

Objective To explore the clinical efficacy of percutaneous vascular forming and stenting in patients with severe stenosis combined with cerebral infarction. Methods The clinical data of 74 patients with severe carotid stenosis combined with cerebral infarction, admitted to our hospital from January 2011 to January 2014, were analyzed; and according to the treatment methods, all patients were divided into operation group (percutaneous angioplasty and stenting, n=37) and non-operation group (conventional therapy, n=37). Follow-up was performed one, 3 and 6 months after discharge, and the prognoses of these patients were evaluated with NIHSS and mini-mental state examination (MMSE). Results Before treatment, the rate of carotid artery stenosis, NIHSS scores and MMSE scores in the two groups showed no significant differences (P>0.05). After treatment, stenosis rate of the operation group ([32.35±4.15]%) was significantly lower than that in the non-operation group ([72.32±7.72]%, P<0.05). One month after treatment, the MMSE scores in the operation group (22.24±2.74) were significantly higher than those in the non-operation group (20.29±3.15, P<0.05). Three months after treatment, the NIHSS scores in the operation group (7.05±1.35) were significantly lower than those in the non-operation group (8.89±1.76, P<0.05). Conclusion Percutaneous vascular forming and stenting can help to achieve favorable outcome in patients with severe stenosis combined with cerebral infarction, which achieves better effect than conventional therapy. Key words: Percutaneous angioplasty; Stenting; Severe carotid stenosis; Infarction