Inhibition of Epstein-Barr Virus by the Triterpenoid Betulin Diphosphate and Uvaol
2004
Betulin, a pentacyclic triterpenoid isolated from the bark of Betula papyrifera. Laboratory synthesized structural analogs were tested for antiviral activities against Epstein-Barr Virus (EBV) by immunofluorescent antiviral assay. Among the several analogs tested, betulin 3,28-diphosphate and uvaol exhibited significant antiviral activities against EBV. The EC 50 of betulin 3,28-diphosphate and uvaol was found to be 0.6 μM and 0.7 μM, respectively.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
0
References
9
Citations
NaN
KQI