Predictive value of CD73 expression in EGFR-mutation positive non-small-cell lung cancer patients received immune checkpoint inhibitors.

Hidenobu Ishii,Koichi Azuma,Takashi Kinoshita,Norikazu Matsuo,Yoshiko Naito,Takaaki Tokito,Kazuhiko Yamada,Tomoaki Hoshino

Predictive value of CD73 expression in EGFR-mutation positive non-small-cell lung cancer patients received immune checkpoint inhibitors.

2018

Hidenobu Ishii
Koichi Azuma
Takashi Kinoshita
Norikazu Matsuo
Yoshiko Naito
Takaaki Tokito
Kazuhiko Yamada
Tomoaki Hoshino

9065Background: CD73 dephosphorylates and converts extracellular adenosine monophosphate to adenosine, leading to immune escape of malignancies. Although epidermal growth factor receptor (EGFR) mut...

Keywords:

Cell
Cancer research
Lung cancer
Pathology
Medicine
Immune checkpoint
Mutation
Epidermal growth factor receptor
Adenosine monophosphate
Adenosine
immune checkpoint inhibitors
predictive value
egfr mutation
Extracellular

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