Relationship between von Willebrand factor and microvascular complications in type 2 diabetic patients

2004 
在109例2型糖尿病患者及56名正常人中,测定血浆von Willebrand因子(vWF)水平.糖尿病患者血浆因子vWF水平较正常人明显升高(P<0.01),糖尿病无微血管并发症患者的尿白蛋白排泄率(UAER)尚在正常范围时已见vWF升高,提示糖尿病患者存在血管内皮功能损伤,vWF升高可能先于UAER出现。
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