Molecular subtypes of triple-negative breast cancer (TNBC) tumor samples obtained before and after neoadjuvant systemic therapy (NST) and relationship between immunomodulatory (IM) gene signature and intensity of tumor-infiltrating lymphocytes (TILs).

Hiroko Masuda,Kenichi Harano,Sakiko Miura,Ying Wang,Yuko Hirota,Oi Harada,Yuki Matsunaga,Bora Lim,Anita L Wood,Anthony Lucci,Napa Parinyanitikul,Hee Jin Lee,Gyungyub Gong,Arvind Rao,Rob Seitz,David R. Hout,Stephan W. Morris,Seigo Nakamura,Savitri Krishnamurthy,Naoto T. Ueno

Molecular subtypes of triple-negative breast cancer (TNBC) tumor samples obtained before and after neoadjuvant systemic therapy (NST) and relationship between immunomodulatory (IM) gene signature and intensity of tumor-infiltrating lymphocytes (TILs).

2018

12069Background: Lehmann et al have identified 4 molecular subtypes of TNBC [basal-like (BL) 1, BL2, mesenchymal (M), and luminal androgen receptor (LAR)] and an IM gene expression signature. Our g...

Keywords:

Gene expression
Androgen receptor
Cancer research
Gene signature
Systemic therapy
Triple-negative breast cancer
Mesenchymal stem cell
Pathology
Medicine
Tumor-infiltrating lymphocytes
luminal androgen receptor

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