Atopic dermatitis prophylactic and / or therapeutic agent

For the purpose of providing concerns prophylactic and / or therapeutic agent for lower high safety atopic dermatitis, such as side effects, extracted result of intensive research, in a polar solvent from pericarp of mangosteen (Garcinia mangostana L.) extract objects were found to prevent or treat atopic dermatitis. That is, the present invention provides a atopic dermatitis prophylactic and / or therapeutic agents comprising extract extracted with a polar solvent from the mangosteen pericarp. The present invention also provides a food containing the above-mentioned atopic dermatitis preventive and / or therapeutic agent.