Antioxidant Therapy for Men With Asymptomatic Prostate Cancer

Abstract : The Department of Defense (DOD) post-doctoral training grant was used to support the career development of 3 individuals, Dr. Thomas Boileau, Dr. Peter Carlton, and Dr. Shihua Wang. Dr. Boileau began his initial training at The Ohio State University under the direction of Dr. Tammy Bray (original mentor on this grant) in the Department of Human Nutrition. He initially completed several projects focusing on the relationships of dietary tomato products, lycopene, and energy intake in prostate cancer, including a clinical study proposed in the original application. Midway through the DOD funding period, his primary mentor Dr. Tammy Bray, was recruited to Oregon State University as Dean. Dr. Boileau joined Dr. Steven K. Clinton's laboratory to complete several of his research projects. He was subsequently able to secure an excellent position in industry where he will continue with his research nutrition and prostate health using dog models. At that time, Dr. Peter Carlton was provided support for a few months on the DOD project but soon thereafter, successfully obtained independent funding to support his salary and career development. Dr. Shihua Wang was added to complete the DOD training grant, including the laboratory studies that were proposed as part of the original application. The results of the studies are described in detail in the attached report. In conclusion, through the DOD support, three investigators have achieved valuable training, particularly in exposure to clinical investigation, and enhanced their career opportunities while generating new knowledge that will enhance future prostate cancer research and patient care.