A NOVEL THREE-STEP HYDROXY-DEAMINATION SEQUENCE : CONVERSION OF LYSINE TO 6-HYDROXYNORLEUCINE DERIVATIVES
1998
Abstract Oxidation of carbamates with catalytic RuO 4 , generated from RuO 2 and NaBrO 3 , provides the corresponding acyl carbamates, which can be reduced with NaBH 4 to provide alcohols. Application of this methodology to L-lysine provides ( S )-6-hydroxynorleucine derivatives.
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
16
References
8
Citations
NaN
KQI