Staphylococcus saprophyticus Sepsis Related to Total Parenteral Nutrition Admixtures Contamination

The aim of this study was to report an outbreak of sepsis related to contamination of total parenteral nutrition (TPN) admixtures with Staphylococcus saprophyticus. A total of four patients developed fever after administration of contaminated TPN. Results of cultures of blood, catheter hubs and tips, and TPN admixtures are presented. The strain responsible for the outbreak was able to grow in vitro in two common TPN formulations. (Journal of Parenteral and Enteral Nutrition17:575-577, 1993)