Repercusiones del síndrome de apneas e hipopneas obstructivas del sueño sobre el rendimiento físico
2005
OBJECTIVES: to determine if Sleep Apnea-Hypopnea Syndrome
(SAHS) is a cause of low physical performance, if physical
performance is improved with nasal CPAP treatment and to study
if there is a relationship between deterioration in physical performance
and increased severity parameters of SAHS .
METHODS: we conducted 32 patients diagnosed with SAHS
(24 patients with severe SAHS measured as an apnea-hypopnea
index �AHI- of ? 50 and 8 with moderate SAHS with AHI between
27-49) to undergo an exercise test on a treadmill up to maximum
force before and after 30 days of treatment with nasal CPAP.
Blood samples were taken at each test (haemogram, proteinogram,
arterial gasometry) and measure of oxygen consumption was registered,
before and after treatment.
RESULTS: patients with severe SAHS reached a maximum
potential of 191,83 ± 54 Watts before and 215 ± 57 Watts after
treatment (p<0.001), while moderate SAHS patients reached
136,75 ± 54 and 145,87 ± 65 (p<0.05) respectively. Maximun oxygen
consumption ranged from 2.851 ± 575 ml/min to 3.220 ± 569
(p<0.001) in patients with severe SAHS and from 2.199± 727
ml/min to 2.330 ± 678 (p<0.05) in moderate SAHS patients. Oxygen
consumption in the anaerobic threshold varied from 1,647±277
ml/min to 2,012±328 (p<0.001) and from 1,316±489 to 1,432±602
(p<0.05) respectively, and the maximum ventilation per minute
from 85.83±19 litres to 92.25±22 (p<0.05) in the severe and with no
significant change in the moderates. The PaO2 increased from
84.87±8.4 to 93.31±6.5 (p<0.05) in the severe and from 79.97±8.6 to
87.8±8.1 (p<0.001) in the moderates, the PaCO2 reduced from
43.33±2.1 to 40.77±2.7 (p<0.05) and from 44.38±3.5 to 42.73±3.4
(p<0.05) respectively, the haemoglobin was 8.41% (p<0.001) and
the haematocrit 3.55% (p<0.001) in the severe. No lineal correlations
were found between the SAHS severity parameters and the
objective deteriorations and improvements.
CONCLUSIONS: In our patients, after a month of treatment
with CPAP, improvement in physical performance was observed,
but no correlation between the the ergometric parameters and
severity of SAHS was found.
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