ApoAI-derived peptide increases glucose tolerance and prevents formation of atherosclerosis in mice
2019
Aims/hypothesis
Finding new treatment alternatives for individuals with diabetes with severe insulin resistance is highly desired. To identify novel mechanisms that improve glucose uptake in skeletal muscle, independently from insulin levels and signalling, we have explored the therapeutic potential of a short peptide sequence, RG54, derived from apolipoprotein A-I (ApoA-I).
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