Horseradish (Moringa oleifera) seed and leaf inclusive diets modulates activities of enzymes linked with hypertension, and lipid metabolites in high-fat fed rats

Abstract This study examined the effects of Horseradish leaves and seeds inclusive diets on angiotensin-I converting enzyme (ACE) and arginase activities and lipid [total cholesterol (TC), triglycerides (TGs), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C)] metabolites in rats fed with high-cholesterol (HC) diet. Animals were divided into seven groups (n = 7) including normal control rats (NC) and untreated hypercholesterolemia rats (HC). Phenolic constituents of the horseradish leaf and seed were determined via high performance liquid chromatography (HPLC-DAD). The result revealed that rats in HC group had higher (p