Imaging observation of acute zonal occult outer retinopathy

Objective To observe the characteristics of acute zonal occult outer retinopathy by the infrared photography (IR), Autofluorescence (AF), Infrared Ray Autofluorescence (IR AF), Fundus Fluoresce Angiography (FFA), Indocyanine Green Angiography (ICGA), optical coherence tomography (OCT). Methods Retrospective observe 12 diagnosed AZOOR cases with IR, AF, IR AF, FFA, ICGA, OCT examination results, find the image feature. Results Twelve eyes had no obvious change in IR; 12 eyes displayed the lesion with clear boundary for strong autofluorescence; 12 eyes had no obvious change in IR AF; 2 eyes had no obvious abnormalities in FFA, 10 eyes had no obvious abnormalities in early and middle FFA, In the late period, the lesion region of the retina showed a slight strong fluorescence; 12 eyes had no obvious change at the early and middle ICGA, In the late period of ICG imaging, after the contrast reversal the lesion was low fluorescence with clear boundary. OCT showed that there was no obvious abnormality in 2 cases, 10 cases showed the inner and outer retinal photoreceptor cells of the regional lesions reflecting weakening, partial deletion. Conclusions After the AZOOR confirmed, spontaneous fluorescence and OCT can be used to observe the disease changes to avoid the damage check. The spontaneous fluorescence photography can be used for the patients whose fundus change is not obvious if the at the condition without ICGA to avoid missed diagnosis. Key words: Acute zonal occult outer retinopathy; Infrared photography; Autofluorescence; FFA; ICGA