Neuroendocrine tumors of the head and neck: SEER analysis of survival and incidence.

e17051 Background: Head and neck neuroendocrine tumors are rare, with limited information regarding frequency, prognosis and significance of site. Methods: A case listing session of SEER 18 (1973-2011) was used to gather staging and outcome information on patients with neuroendocrine tumors in the head/neck, identifying 1,346 cases. We used SEER*Stat 8.1.15, Microsoft Excel and STATA software for analysis. Kaplan Meier method and log-rank test were used to determine survival by site and metastatic status. Results: 1,346 patients with head and neck neuroendocrine tumors were identified. Of these 549 had small cell carcinoma, 473 had neuroendocrine tumor NOS, 271 had large cell carcinoma and 53 had carcinoid tumor. Incidence by site was: 29% salivary glands, 25% larynx/hypopharynx, 18% nasopharynx, 16% paranasal sinuses, and 13% mouth/oropharynx. 1,288 patients had cancer survival time/vital status information. Estimated median survival for all patients was 25 months. 530 patients had metastatic status reco...