POLYUNSATURATED FATTY ACID INTAKE AND ITSCORRELATION WITH POSITIVE AND NEGATIVE SYNDROME SCALE (PANSS) IN SCHIZOPHRENIA PATIENT
2021
Background/Aims: The treatment of schizophrenia is commonly
viewed from a pharmacological and social perspective, but
issues
of nutrient intake are seldom examined. However, the various
study reported that polyunsaturated fatty acids (PUFAs) concentration
is reduced in the plasma of schizophrenic patients.
Therefore
PUFAs intake may have a correlation with psychiatric
symptoms
in schizophrenia patients. This study aimed to assess
the
PUFAs intake of schizophrenic patients and its correlation
with
The Positive and Negative Syndrome Scale.
Methods:
This
cross-sectional
study was conducted on 63 schizophrenia hospitalized
patients in Ernaldi Bahar Hospital, South Sumatra, Indonesia.
The
psychiatric symptoms were determined using the validated
Indonesian
version of PANSS. Dietary intake was assessed using a
3-day
food weighing. Correlation between variables was determined
using the Spearman Correlation Coefficient.
Results:
The
result
showed a significant negative correlation between omega-3
fatty acids and Positive scale, Negative Scale, General psychopa-
thology and risk of aggression with r = –0.345, r= –0.408, r= –0.483,
and r= –0.406 respectively (p < 0.01). The omega-6 fatty acids in-take were negatively correlated with Positive scale, Negative Scale,
General psychopathology and risk of aggression with r = –0.390,
r = –0.496, r = –0.525, and r = –0.389 respectively (p < 0.01). A
statistically significant correlation was seen between ratio of omega-6/omega-3
and Positive scale, Negative Scale, General psychopathology
and risk of aggression with r =
0.249, r =
0.256, r =
0.356,
r =
0.343 respectively (p < 0.01).
Conclusion:
These findings suggest
that increasing PUFAs intake might have a positive health
outcome
in schizophrenia patient.
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