Gas chromatography in combination with fast high-resolution time-of-flight mass spectrometry: Technical overview and perspectives for data visualization

Abstract Time-of-flight mass spectrometry combines fast acquisition speed with the ability to collect full spectral information and over the last years high mass resolution instrumentation become available for customers. These features make TOFMS very interesting for the hyphenation with fast or comprehensive two-dimensional gas chromatography. This publication reviews the technical progress of TOF-techniques with the focus on their compatibility with fast and ultra-fast chromatographic separations. A special focus is put on ionization techniques and data visualization approaches, covering related review article as well as selected primary literature and studies.