Design, Synthesis and Antibacterial Activity of Novel Ketolides Bearing an Aryltetrazolyl-Substituted Alkyl Side Chain.

Qiu-Ling Song,Bao-Qin Guo,Wen Zhang,Ping Lan,Ping-Hua Sun,Wei-Min Chen

Design, Synthesis and Antibacterial Activity of Novel Ketolides Bearing an Aryltetrazolyl-Substituted Alkyl Side Chain.

2012

Qiu-Ling Song
Bao-Qin Guo
Wen Zhang
Ping Lan
Ping-Hua Sun
Wei-Min Chen

A series of novel C-11,12 cyclic carbamate ketolides (17 examples) are synthesized from clarithromycin and evaluated for their antibacterial activities.

Keywords:

Antibacterial activity
Side chain
Alkyl
Clarithromycin
Carbamate
Organic chemistry
Chemistry
alkyl side chain
design synthesis

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