Anticancer agents to form a self-aggregates - chitosan complex and its manufacturing method

The present invention, anticancer agents to form a self-aggregates - relates chitosan complex and its manufacturing method. More particularly, the present invention is composed of a hydrophobic anticancer drug and hydrophilic chitosan, anticancer agents to form a self-aggregates in an aqueous medium - relates chitosan complex and its manufacturing method. Anticancer agents of the present invention - Chitosan complex not only act selectively against the tumor tissue to be targeted, sustained-release drug over a prolonged period of time. Moreover, anticancer agents - chitosan complex by the addition of anti-cancer agents in the interior of the self-aggregates, usually can increase the content of the drug being limited to the chemical bond. Thus, the inventive anticancer agents - chitosan complex can be usefully used in cancer chemotherapy.