Syntheses of Prodelphinidin B1, B2, and B4 and Their Antitumor Activities Against Human PC-3 Prostate Cancer Cell Lines.

Wataru Fujii,Kazuya Toda,Kiriko Matsumoto,Koichiro Kawaguchi,Sei-ichi Kawahara,Yasunao Hattori,Hiroshi Fujii,Hidefumi Makabe

Syntheses of Prodelphinidin B1, B2, and B4 and Their Antitumor Activities Against Human PC-3 Prostate Cancer Cell Lines.

2014

Wataru Fujii
Kazuya Toda
Kiriko Matsumoto
Koichiro Kawaguchi
Sei-ichi Kawahara
Yasunao Hattori
Hiroshi Fujii
Hidefumi Makabe

The title compounds are prepared via Lewis acid-mediated equimolar condensation of a gallocatechin and/or epigallocatechin nucleophile with gallocatechin and/or epigallocatechin electrophiles.

Keywords:

Prodelphinidin
Gallocatechin
Electrophile
Prostate cancer
Nucleophile
Organic chemistry
Chemistry
Cell culture
prostate cancer cell

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