What are the best treatments for benign migratory glossitis

Data sources PubMed, The Cochrane Library, Embase, Science Direct, Scopus, Web of Science and Google Scholar databases. Study selection English language studies reporting on treatment of symptomatic benign migratory glossitis (BMG) in children and adults were considered. Data extraction and synthesis Two reviewers independently selected studies with a single author extracting data subsequently verified by a second reviewer. A third reviewer was available to resolve discrepancies. A narrative summary of the findings was presented. Results Eleven studies involving a total of 150 patients contributed to the review. A majority (eight) were considered to be of very low quality, one of low quality, one of moderate quality and one of high quality. A range of treatments were employed, the most common being triamcinolone acetonide 0.1% (n = 2), topical tacrolimus 0.1% (n = 2), topical diphenhydramine (n = 2), and nutritional supplements (n = 2) Conclusions There is substantial heterogeneity in the available studies providing very low-quality evidence for the treatment of symptomatic benign migratory glossitis.