Title Tumor-containing CEA in Colon Cancers

ABSTRACT : Carcinoembryonic antigen (CEA) in serum and fresh cancer tissue taken at surgery was measured and analyzed in terms of the disease stage. The CEA level in serum (s-CEA ) has become higher with advance in the disease stage. However, in stage V it was lowered as well as CEA level in cancer mass (ca-CEA). It is suggested that S-CEA is influenced by cancer invasion into the vessel wall, tumor necrosis and/or degeneration which ca-CEA may well be migrated from the tumor cells. .INTRODUCTION The measurement of carcinoembryonic anti-gen (CEA) was of use to detect colon cancer and its recurrence in follow-up study. Recently it was defined that serum CEA lev-els were not specific to the patients with colon cancer and these were increased colon cancer as well as breast and gastric one. In the present study, the clinical significance of CEA in patients with colon cancer was eval-uated as compared between CEA in serum and tissues including cancer mass. MATERIAL AND METHOD Fifty-nine cases of colon cancer treated in our clinics were eligible in this study, 13 of