Method for detection of risk of heredital determination of breast cancer based on anamnetic data

2016 
FIELD: medicine. SUBSTANCE: before special treatment, the patient is questioned on the basis of the following characteristics: the patient's age, the number of abortions, the number of pregnancies, the age of menopause, the duration of smoking, the number of breastfeedings, the duration of breastfeeding, and then the prognostic factor (PC) is calculate, namely: ≤42 years old PC (+) 10, more than 42 years old PC (-) 7.7; number of abortions ≤1 PC (+) 2.0, more than 1 PC (-) 2.3; if the number of pregnancies is ≤2 PC (+) 3.6, more than 2 PC (-) 2.6; if the age of is menopause ≤41 year of PC (+) 3.6, over 41 years of PC (-) 3.7, if there is no menopause, this factor is not taken into account; at duration of smoking equal to ≤9 years PC (+) 3, more than 9 years PC (-) 5.4, if the woman does not smoke, then 0; if the number of breastfeeding is ≤1 PC (+) 4, more than 1 PC (-) 7; at the duration of breastfeeding of ≤6 months PC (+) 5.4, more than 6 months PC (-) 4.6; further, the total PC is determined, and for PC ≥ (+) 18, high risk of hereditary breast cancer, and at PK < (+) 18,no risk of genetic determination of breast cancer is determined. EFFECT: invention allows to take into account the high risk of an inherited predisposition to breast cancer and timely connect diagnostic activities to identify the patient's health status and implement preventive measures of prevention or treatment. 5 tbl, 2 ex
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