PEPTIDE NEUROHUMORS IN THE BRAIN.

Abstract : Research progress is reported, along with a list of papers and communications published. Significant amounts of peptide substances displaying neurohypophysial activity were found to exist in the human hypothalamus. Peptides having oxytocinand vasopressin-like activity were found in the antero hypophysis. From diverse areas of the brain, it was found possible to obtain extracts capable of inducing depletion of the ovarian ascorbic acid in rats prepared according to the Parlow test. Studies were carried out on an active material which displays peptide nature and which induces pharmacological effects on diverse biological preparations. An LH activity was found in the human hypothalamus.