Multiparticulate dosage form of at least two different coating pellet form

The present invention, the core has a different polymeric coating to release the drug in the drug and different pH values ​​were suitable for uniformly release the drug in the small intestine and large intestine, multiparticulate dosage form comprising at least one pellet form on. In this dosage form, it comprises an outer polymer coating pellets A is rapidly dissolved inside the polymeric coating and from about pH5.5 or higher which enables continuous release of the drug. Pellets B, in USP release test, less than 20% of the pharmaceutically active substance after 6 hours at pH 6.8, with a polymeric coating that releases more than 50% of the drug active substance after 6 hours at pH 7.2. The present invention further relates to the use of pellets A and B to the multiparticulate dosage form preparation and the dosage form.