AN ECONOMICAL REGIMEN OF HUMAN DIPLOID CELL STRAIN ANTI-RABIES VACCINE FOR POST-EXPOSURE PROPHYLAXIS

One hundred and seventy-nine Thai subjects with no history of rabies vaccination were inoculated either with a) Semple vaccine alone, b) one of various economical, candidate regimens for human diploid cell strain rabies vaccine (HDCSV) alone, c) or vaccine and human rabies immune globulin (HRIG) given at a dosage of 40 IU/kg on day 0. Rabies lgG antibodies were measured by enzyme immunoassay (Elisa) on samples taken from each group of volunteers on days 0, 7, 14, 28, 91 and, for some groups, day 182.