Frailty and comprehensive geriatric assessment organized as CGA-ward or CGA-consult for older adult patients in the acute care setting : a systematic review and meta-analysis

Abstract Background With worldwide population aging, increasing numbers of people need hospital care. Evidence suggests comprehensive geriatric assessment (CGA) is superior to usual care. Objective To summarize the evidence for the effects of CGA in frail and moderately frail patients compared with usual care in acute care settings. Data sources CINAHL, PsycInfo, Cochrane Library, EMBASE, and PubMed were searched in October 2011, January 2013, and February 2015. Study eligibility Randomized controlled trials. Participants Older adults aged ≥ 65 years who were admitted to hospital with a complex condition, divided into frail and moderately frail groups. Intervention CGA. Control Usual care. Outcomes Change in housing, personal activities of daily living (PADL), instrumental activities of daily living (IADL), readmission, cognitive function, depression, quality-of-life care-giver burden, and mortality. Study appraisal and synthesis The grading of recommendations assessment development and evaluation (GRADE) system to assess the quality of evidence and PRISMA-guidelines for meta-analyses and reviews. Continuous data were presented as standardized mean differences and dichotomous data were presented as risk differences. Results Twenty-nine articles based on 17 unique studies (6005 patients in total). CGA was categorized as CGA- ward or CGA- consult . In the frail group, CGA- ward was superior to usual care for change in housing, PADL, and depression. CGA- consult was superior to usual care for PADL and IADL in the moderately frail group. Conclusion There was a stronger effect for frail older adults and CGA- ward compared with usual care. This highlights the importance of detecting frailty. However, the degree of evidence was limited.